Calbindin D-28K Antibody (FGF2/7364)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-23616

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2 kappa Clone # FGF2/7364

Concentration

0.2 mg/ml

View all Calbindin D-28K Antibodies »

Product Specifications

Immunogen

Recombinant fragment (around aa 7-96) of human Calbindin D-28K protein (exact sequence is proprietary)

Localization

Nucleus. Cytoplasm.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2 kappa

Description

Store at 2 to 8C. Non-hazardous. No MSDS required.

Scientific Data Images for Calbindin D-28K Antibody (FGF2/7364)

Calbindin D-28K Antibody (FGF2/7364)

Immunohistochemistry-Paraffin: Calbindin D-28K Antibody (FGF2/7364) [NBP3-23616] -

Formalin-fixed, paraffin-embedded human placenta stained with Calbindin D-28K antibody (FGF2/7364). Inset: PBS instead of primary antibody; secondary only negative control.

Applications for Calbindin D-28K Antibody (FGF2/7364)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2ug/ml
Application Notes
Immunohistochemistry-Paraffin: 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Calbindin D-28K

Calbindin D28k is a member of a large family of intracellular calcium-binding proteins, containing EF-hand calcium binding motifs, and related to calmodulin and troponin-C. The biological roles of Calbindin D28k include calcium regulation and calcium-dependent signalling in neurons and during development. Decreases in Calbindin D28k abundance, or loss of Calbindin D28k immunoreactivity, is found in models of neurological disorders such as epilepsy, and in neurodegenerative diseases. Calbindin antibody is often used as a marker for cerebellum Purkinje cells.

Alternate Names

CAB27, CALB, calbindin, calbindin 1, (28kD), calbindin 1, 28kDa, Calbindin D28, D-28K, RTVL-H protein, Vitamin D-dependent calcium-binding protein, avian-type

Gene Symbol

CALB1

Additional Calbindin D-28K Products

Product Documents for Calbindin D-28K Antibody (FGF2/7364)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Calbindin D-28K Antibody (FGF2/7364)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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