Calcitonin R Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88041

Novus Biologicals, part of Bio-Techne
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NBP1-88041
NBP1-88041-25ul
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Calcitonin R Antibodies »

Product Summary for Calcitonin R Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: AFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPENNRTWSNYTMCNAFTPE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Calcitonin R Antibody

Immunohistochemistry-Paraffin: Calcitonin R Antibody [NBP1-88041]

Immunohistochemistry-Paraffin: Calcitonin R Antibody [NBP1-88041]

Immunohistochemistry-Paraffin: Calcitonin R Antibody [NBP1-88041] - Staining of human colon.
Immunohistochemistry-Paraffin: Calcitonin R Antibody [NBP1-88041]

Immunohistochemistry-Paraffin: Calcitonin R Antibody [NBP1-88041]

Immunohistochemistry-Paraffin: Calcitonin R Antibody [NBP1-88041] - Staining of human hypothalamus shows strong membranous positivity in neuronal cells and neuronal projections.
Immunohistochemistry-Paraffin: Calcitonin R Antibody [NBP1-88041]

Immunohistochemistry-Paraffin: Calcitonin R Antibody [NBP1-88041]

Immunohistochemistry-Paraffin: Calcitonin R Antibody [NBP1-88041] - Staining of human cerebral cortex, colon, hypothalamus and testis using Anti-CALCR antibody NBP1-88041 (A) shows similar protein distribution across tissues to independent antibody NBP2-68772 (B).
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Applications for Calcitonin R Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Calcitonin R

The Calcitonin Receptor inhibits bone resorption. This receptor is expressed during development and is involved in morphogenesis. Three alternatively spliced Calcitonin Receptor isoforms have been identified. In addition to binding calcitonin, the Calcitonin Receptor can complex with RAMP3 (receptor activity modifying protein) to bind amylin, which regulates pancreatic islet function and is involved in Type II diabetes. The Calcitonin Receptor has been reported in artery, blood, bone, brain, kidney, lung, placenta, prostate, skeletal muscle, and thyroid. ESTs have been isolated from bone, embryo, kidney, and melanocyte/uterus/fetal heart libraries.

Long Name

Calcitonin Receptor

Alternate Names

CalcitoninR, CALCR, CT-R

Entrez Gene IDs

799 (Human)

Gene Symbol

CALCR

UniProt

P30988 (Human)

Additional Calcitonin R Products

Product Documents for Calcitonin R Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Calcitonin R Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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