CALHM1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83930

Novus Biologicals, part of Bio-Techne
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NBP1-83930
NBP1-83930-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CALHM1 Antibodies »

Product Summary for CALHM1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: CTEHAKAFAKVCIQQFFEAMNHDLELGHTHGTLATAPASAAAPTTPDGAEEEREKLRGITDQGTMNRLLTSWHKCKPPLRLGQEEPPLMGNGW

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (82%), Rat (80%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CALHM1 Antibody

Immunohistochemistry-Paraffin: CALHM1 Antibody [NBP1-83930]

Immunohistochemistry-Paraffin: CALHM1 Antibody [NBP1-83930]

Immunohistochemistry-Paraffin: CALHM1 Antibody [NBP1-83930] - Staining of human cerebral cortex shows cytoplasmic positivity in neurons.

Applications for CALHM1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CALHM1

CALHM1 controls cytosolic calcium permeability and cytosolic calcium concentration. It controls amyloid precursor protein (APP) proteolysis and aggregated amyloid-beta (Abeta) peptides levels in a calcium dependent manner. However, no association between CALHM1 and Alzheimer's risk is unclear. Member of the FAM26 family of proteins. CALHM1 is predominantly expressed in the adult brain. It has also been detected in retinoic acid differentiated SH-SY5Y cells. Also colocalizes with HSPA5 at the endoplasmic reticulum.

Alternate Names

calcium homeostasis modulator 1, FAM26Ccalcium homeostasis modulator protein 1, family with sequence similarity 26, member C, MGC39514, MGC39617, Protein FAM26C

Gene Symbol

CALHM1

Additional CALHM1 Products

Product Documents for CALHM1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CALHM1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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