Calpain S1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15677

Novus Biologicals, part of Bio-Techne
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NBP2-15677
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Calpain S1 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human Calpain S1. The exact sequence is proprietary.

Localization

Cytoplasm; Cell membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Calpain S1 Antibody

Western Blot: Calpain S1 Antibody [NBP2-15677]

Western Blot: Calpain S1 Antibody [NBP2-15677]

Western Blot: Calpain S1 Antibody [NBP2-15677] - Sample (30 ug of whole cell lysate) A: 293T 12% SDS PAGE gel, diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: Calpain S1 Antibody [NBP2-15677]

Immunocytochemistry/ Immunofluorescence: Calpain S1 Antibody [NBP2-15677]

Immunocytochemistry/Immunofluorescence: Calpain S1 Antibody [NBP2-15677] - \Calpain S1 antibody detects Calpain S1 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in iced-cold MeOH for 5 min. Green: Calpain S1 protein stained by Calpain S1 antibody diluted at 1:500. Blue: Hoechst 33343 staining.
Immunohistochemistry-Paraffin: Calpain S1 Antibody [NBP2-15677]

Immunohistochemistry-Paraffin: Calpain S1 Antibody [NBP2-15677]

Immunohistochemistry-Paraffin: Calpain S1 Antibody [NBP2-15677] - Immunohistochemical analysis of paraffin-embedded LUNG ADC, using antibody at 1:100 dilution.

Applications for Calpain S1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Calpain S1

This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

Alternate Names

Calcium-activated neutral proteinase small subunit, Calcium-dependent protease small subunit 1, calcium-dependent protease, small subunit, calpain 4, small subunit (30K), Calpain regulatory subunit, calpain small subunit 1, calpain, small polypeptide, CALPAIN4, CANP, CANPS, CAPN4, CDPS, CSS1, epididymis secretory sperm binding protein

Gene Symbol

CAPNS1

UniProt

P04632 (Human)

Additional Calpain S1 Products

Product Documents for Calpain S1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Calpain S1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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