Calsequestrin 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87304

Novus Biologicals, part of Bio-Techne
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NBP1-87304
NBP1-87304-25ul
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (95%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Calsequestrin 2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: EEGLNFPTYDGKDRVVSLSEKNFKQVLKKYDLLCLYYHEPVSSDKVTQKQFQLKEIVLELVAQVL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Calsequestrin 2 Antibody

Immunohistochemistry-Paraffin: Calsequestrin 2 Antibody [NBP1-87304]

Immunohistochemistry-Paraffin: Calsequestrin 2 Antibody [NBP1-87304]

Immunohistochemistry-Paraffin: Calsequestrin 2 Antibody [NBP1-87304] - Staining in human heart muscle and skin tissues using anti-CASQ2 antibody. Corresponding CASQ2 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Calsequestrin 2 Antibody [NBP1-87304]

Immunohistochemistry-Paraffin: Calsequestrin 2 Antibody [NBP1-87304]

Immunohistochemistry-Paraffin: Calsequestrin 2 Antibody [NBP1-87304] - Staining of human heart muscle, lymph node, skeletal muscle and skin using Anti-CASQ2 antibody NBP1-87304 (A) shows similar protein distribution across tissues to independent antibody NBP2-33747 (B).
Western Blot: Calsequestrin 2 Antibody [NBP1-87304]

Western Blot: Calsequestrin 2 Antibody [NBP1-87304]

Western Blot: Calsequestrin 2 Antibody [NBP1-87304] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-93
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Applications for Calsequestrin 2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Calsequestrin 2

Calsequestrin 2 is encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.

Alternate Names

calsequestrin 2 (cardiac muscle), calsequestrin 2, fast-twitch, cardiac muscle, Calsequestrin, cardiac muscle isoform, calsequestrin-2, FLJ26321, FLJ93514, PDIB2

Gene Symbol

CASQ2

Additional Calsequestrin 2 Products

Product Documents for Calsequestrin 2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Calsequestrin 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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