CAR/NR1I3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00009970-B01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CAR/NR1I3 Antibodies »

Product Specifications

Immunogen

NR1I3 (NP_001070948.1, 1 a.a. - 352 a.a.) full-length human protein. MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS

Reactivity Notes

This product is reactive against Human.

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for CAR/NR1I3 Antibody

Western Blot: CAR/NR1I3 Antibody [H00009970-B01P]

Western Blot: CAR/NR1I3 Antibody [H00009970-B01P]

Western Blot: CAR/NR1I3 Antibody [H00009970-B01P] - Analysis of NR1I3 expression in transfected 293T cell line by NR1I3 polyclonal antibody. Lane 1: NR1I3 transfected lysate(38.72 KDa). Lane 2: Non-transfected lysate.

Applications for CAR/NR1I3 Antibody

Application
Recommended Usage

Western Blot

1:100-1:2000
Application Notes
This antibody is useful for Western Blot

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CAR/NR1I3

This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Long Name

Constitutive Androstane Receptor

Alternate Names

MB67, NR1I3

Gene Symbol

NR1I3

UniProt

NP_001070948.1 (Human)

Additional CAR/NR1I3 Products

Product Documents for CAR/NR1I3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CAR/NR1I3 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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