carabin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-76349

Novus Biologicals, part of Bio-Techne
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NBP2-76349
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Canine (100%), Porcine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Flow Cytometry, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all carabin Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-PRRKPQTRGKTFH corresponding to internal region according to NP_940919.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for carabin Antibody

Western Blot: carabin Antibody [NBP2-76349]

Western Blot: carabin Antibody [NBP2-76349]

Western Blot: carabin Antibody [NBP2-76349] - Staining of Human Spleen (A) and Mouse Thymus (B) lysate (35 ug protein in RIPA buffer). Antibody at 2 ug/mL. Detected by chemiluminescence.
Flow Cytometry: carabin Antibody [NBP2-76349]

Flow Cytometry: carabin Antibody [NBP2-76349]

Flow Cytometry: carabin Antibody [NBP2-76349] - Paraformaldehyde fixed Jurkat cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.
Western Blot: carabin Antibody [NBP2-76349]

Western Blot: carabin Antibody [NBP2-76349]

Western Blot: carabin Antibody [NBP2-76349] - Staining of Jurkat with antibody at 0.5 ug/mL (A), PBM with antibody at 0.3 ug/mL (B) and negative control A431 (C) cell lysate (35 ug protein in RIPA buffer). Detected by chemiluminescence.

Applications for carabin Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:28000
Application Notes
WB: Preliminary experiments in human tonsil, thymus and peripheral mononucleocytes lysates gave no specific signal but low background.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: carabin

Carabin is an endogenous inhibitor of calcineurin (see MIM 114105) that also inhibits the Ras (see MIM 190020) signaling pathway through its intrinsic Ras GTPase-activating protein activity (Pan et al., 2007 [PubMed 17230191]).[supplied by OMIM]

Alternate Names

carabin, FLJ00332, MGC46488, TBC1 domain family member 10C, TBC1 domain family, member 10C

Gene Symbol

TBC1D10C

Additional carabin Products

Product Documents for carabin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for carabin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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