Carboxypeptidase M Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87403

Novus Biologicals, part of Bio-Techne
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NBP1-87403
NBP1-87403-25ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human, Mouse

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Knockdown Validated, Western Blot

Cited:

Knockdown Validated, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Carboxypeptidase M Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVS

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (88%). Use in Mouse reported in scientific literature (PMID:31401267).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Carboxypeptidase M Antibody

Western Blot: Carboxypeptidase M Antibody [NBP1-87403]

Western Blot: Carboxypeptidase M Antibody [NBP1-87403]

Western Blot: Carboxypeptidase M Antibody [NBP1-87403] - Analysis in human cell line THP-1.
Immunohistochemistry-Paraffin: Carboxypeptidase M Antibody [NBP1-87403]

Immunohistochemistry-Paraffin: Carboxypeptidase M Antibody [NBP1-87403]

Immunohistochemistry-Paraffin: Carboxypeptidase M Antibody [NBP1-87403] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: Carboxypeptidase M Antibody [NBP1-87403]

Immunohistochemistry-Paraffin: Carboxypeptidase M Antibody [NBP1-87403]

Immunohistochemistry-Paraffin: Carboxypeptidase M Antibody [NBP1-87403] - Staining of human endometrium shows strong positivity in apical membrane in glandular cells.
View 2 more images

Applications for Carboxypeptidase M Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Knockdown Validated

Reactivity reported in (PMID: 31401267)

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Carboxypeptidase M

The protein encoded by the Carboxypeptidase M gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq]

Alternate Names

CPM

Gene Symbol

CPM

Additional Carboxypeptidase M Products

Product Documents for Carboxypeptidase M Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Carboxypeptidase M Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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