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CARF/CDKN2AIP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-57236

Novus Biologicals, part of Bio-Techne
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NBP1-57236

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

Product Specifications

Immunogen

Synthetic peptides corresponding to CARF The peptide sequence was selected from the C terminal of CARF. Peptide sequence AIEALKATLDVFFVPLKELADLPQNKSSQESIVCELRCKSVYLGTGCGKS. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for CARF/CDKN2AIP Antibody

Western Blot: CARF/CDKN2AIP Antibody [NBP1-57236]

Western Blot: CARF/CDKN2AIP Antibody [NBP1-57236]

Western Blot: CARF/CDKN2AIP Antibody [NBP1-57236] - Jurkat cell lysate, Antibody Titration: 0.3125ug/ml
Immunohistochemistry-Paraffin: CARF/CDKN2AIP Antibody [NBP1-57236]

Immunohistochemistry-Paraffin: CARF/CDKN2AIP Antibody [NBP1-57236]

Immunohistochemistry-Paraffin: CARF/CDKN2AIP Antibody [NBP1-57236] - Human Muscle Tissue, Skeletal muscle cells (Indicated with Arrows) 4-8ug/ml.

Applications for CARF/CDKN2AIP Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CARF

CARF was first cloned as a novel binding partner of ARF from a yeast-interactive screen. CARF and ARF colocalize in the perinucleolar region and have a collaborative function. In the nucleoplasm, CARF interacts with p53 and enhances its function. The p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2.

Long Name

Collaborates/Cooperates With ARF [Alternate Reading Frame] Protein

Alternate Names

CDKN2AIP

Gene Symbol

CDKN2AIP

UniProt

Additional CARF Products

Product Documents for CARF/CDKN2AIP Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CARF/CDKN2AIP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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