Casein Kinase 1 alpha Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57137

Novus Biologicals, part of Bio-Techne
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NBP2-57137
NBP2-57137-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Casein Kinase 1 alpha Antibodies »

Product Summary for Casein Kinase 1 alpha Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: TLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Casein Kinase 1 alpha Antibody

Immunocytochemistry/ Immunofluorescence: Casein Kinase 1 alpha Antibody [NBP2-57137]

Immunocytochemistry/ Immunofluorescence: Casein Kinase 1 alpha Antibody [NBP2-57137]

Immunocytochemistry/Immunofluorescence: Casein Kinase 1 alpha Antibody [NBP2-57137] - Staining of human cell line PC-3 shows localization to cytosol. Antibody staining is shown in green.

Applications for Casein Kinase 1 alpha Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Casein Kinase 1 alpha

Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase Ialpha, Igamma, Idelta and Iepisilon, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an alpha2beta2 or an alphaalpha'beta2 structure. The a catalytic subunit is stimulated by the beta regulatory subunit, which undergoes autophosphorylation. Casein kinase II activity is high in the cytosol and nucleus of proliferating and differentiating cells. Casein kinase II is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.

Alternate Names

CSNK1A1, HLCDGP1

Gene Symbol

CSNK1A1

Additional Casein Kinase 1 alpha Products

Product Documents for Casein Kinase 1 alpha Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Casein Kinase 1 alpha Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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