Catenin alpha 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-2917

Novus Biologicals, part of Bio-Techne
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NB100-2917
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Catenin alpha 1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-KREKQDETQTKIK corresponding to internal region according to NP_001894.2.

Epitope

C-KREKQDETQTKIK

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Catenin alpha 1 Antibody

Western Blot: Catenin alpha 1 Antibody [NB100-2917]

Western Blot: Catenin alpha 1 Antibody [NB100-2917]

Western Blot: Catenin alpha 1 Antibody [NB100-2917] - Analysis of Catenin alpha 1 using NB100-2917 at 1ug/mL in human colon lysate (35 ug protein in RIPA buffer).
Immunohistochemistry-Paraffin: Catenin alpha 1 Antibody [NB100-2917]

Immunohistochemistry-Paraffin: Catenin alpha 1 Antibody [NB100-2917]

Immunohistochemistry-Paraffin: Catenin alpha 1 Antibody [NB100-2917] - Staining of paraffin embedded human uterus. Antibody at 3.75 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Western Blot: Catenin alpha 1 Antibody [NB100-2917]

Western Blot: Catenin alpha 1 Antibody [NB100-2917]

Western Blot: Catenin alpha 1 Antibody [NB100-2917] - HEK293 overexpressing Human CTNNA1 and probed with (mock transfection in first lane).
View 1 more images

Applications for Catenin alpha 1 Antibody

Application
Recommended Usage

Immunohistochemistry

3.75 ug/mL

Immunohistochemistry-Paraffin

3.75 ug/mL

Peptide ELISA

Detection limit 1:32000

Western Blot

1 - 3 ug/mL
Application Notes
WB: Approx. 100 kDa band observed in human colon and human skin lysates (calculated MW of 100 kDa band according to NP_001894.2).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Catenin alpha 1

The centaurin alpha 1 protein is a high affinity PtdIns(3,4,5)P3 binding protein enriched in brain. By acting as a GTPase activating protein for ADP ribosylation factor 6 (ARF6), centaurin alpha 1 is able to switch off ARF6 and inhibit its ability to mediate beta 2 adrenoceptor internalization and negatively regulates ARF6 activity by functioning as an in vivo PIP3 dependent ARF6 GAP.

Alternate Names

Alpha E-catenin, alpha-catenin, alpha-E-catenin, alphaE-catenin, Cadherin-associated protein, CAP102, catenin (cadherin-associated protein), alpha 1 (102kD), catenin (cadherin-associated protein), alpha 1, 102kDa, catenin alpha-1, FLJ36832, FLJ52416, Renal carcinoma antigen NY-REN-13

Entrez Gene IDs

1495 (Human); 12385 (Mouse); 307505 (Rat)

Gene Symbol

CTNNA1

UniProt

NP_001894.2 (Human)

Additional Catenin alpha 1 Products

Product Documents for Catenin alpha 1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Catenin alpha 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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