Cathepsin K Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-58351

Novus Biologicals, part of Bio-Techne
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NBP2-58351
NBP2-58351-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cathepsin K Antibodies »

Product Summary for Cathepsin K Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: LAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASF

Reactivity Notes

Mouse 83%, Rat 85%

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cathepsin K Antibody

Immunocytochemistry/ Immunofluorescence: Cathepsin K Antibody [NBP2-58351]

Immunocytochemistry/ Immunofluorescence: Cathepsin K Antibody [NBP2-58351]

Immunocytochemistry/Immunofluorescence: Cathepsin K Antibody [NBP2-58351] - Staining of human cell line SK-MEL-30 shows localization to nucleoplasm & vesicles.

Applications for Cathepsin K Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cathepsin K

Cathepsin K is encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq]

Alternate Names

CTS02, CTSK, CTSO1, CTSO2, PKND, PYCD

Gene Symbol

CTSK

Additional Cathepsin K Products

Product Documents for Cathepsin K Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cathepsin K Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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