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Cathepsin S Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85807

Novus Biologicals, part of Bio-Techne
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NBP1-85807
NBP1-85807-25ul

Key Product Details

Validated by

Knockout/Knockdown

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Knockdown Validated, Western Blot

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Cathepsin S Antibody

Western Blot: Cathepsin S Antibody [NBP1-85807]

Western Blot: Cathepsin S Antibody [NBP1-85807]

Western Blot: Cathepsin S Antibody [NBP1-85807] - Analysis in U-87MG ATCC cells transfected with control siRNA, target specific siRNA probe #1,. Remaining relative intensity is presented. Loading control: Anti-PPIB.
Immunocytochemistry/ Immunofluorescence: Cathepsin S Antibody [NBP1-85807]

Immunocytochemistry/ Immunofluorescence: Cathepsin S Antibody [NBP1-85807]

Immunocytochemistry/Immunofluorescence: Cathepsin S Antibody [NBP1-85807] - Staining of human cell line U-2 OS shows localization to vesicles. Antibody staining is shown in green.
Cathepsin S Antibody

Immunohistochemistry-Paraffin: Cathepsin S Antibody [NBP1-85807] -

Immunohistochemistry-Paraffin: Cathepsin S Antibody [NBP1-85807] -Staining of human lymph node shows strong cytoplasmic granular positivity in a subset of non-germinal center cells.and germinal center cells

Applications for Cathepsin S Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cathepsin S

Cathepsin S is encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Transcript variants utilizing alternative polyadenylation signals exist for this gene.

Alternate Names

CTSS

Entrez Gene IDs

1520 (Human)

Gene Symbol

CTSS

UniProt

Additional Cathepsin S Products

Product Documents for Cathepsin S Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Cathepsin S Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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