Caveolin-2 Antibody (8I4U7)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16502

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-16502-100ul
NBP3-16502-20ul
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 8I4U7

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Caveolin-2 Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Caveolin-2 (P51636). MGLETEKADVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHLKLGFEDVIAEPVTTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFIA

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Caveolin-2 Antibody (8I4U7)

Western Blot: Caveolin-2 Antibody (8I4U7) [NBP3-16502]

Western Blot: Caveolin-2 Antibody (8I4U7) [NBP3-16502]

Western Blot: Caveolin-2 Antibody (8I4U7) [NBP3-16502] - Western blot analysis of extracts of 293T cells, using Caveolin-2Rabbit mAb (NBP3-16502) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Immunohistochemistry-Paraffin: Caveolin-2 Antibody (8I4U7) [NBP3-16502]

Immunohistochemistry-Paraffin: Caveolin-2 Antibody (8I4U7) [NBP3-16502]

Immunohistochemistry-Paraffin: Caveolin-2 Antibody (8I4U7) [NBP3-16502] - Immunohistochemistry of paraffin-embedded human esophageal cancer using Caveolin-2Rabbit mAb (NBP3-16502) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Western Blot: Caveolin-2 Antibody (8I4U7) [NBP3-16502]

Western Blot: Caveolin-2 Antibody (8I4U7) [NBP3-16502]

Western Blot: Caveolin-2 Antibody (8I4U7) [NBP3-16502] - Western blot analysis of extracts of Mouse lung, using Caveolin-2Rabbit mAb (NBP3-16502) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
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Applications for Caveolin-2 Antibody (8I4U7)

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunoprecipitation

1:500 - 1:1000

Western Blot

1:500 - 1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Caveolin-2

Caveolae are cholesterol/sphingolipid-rich microdomains of the plasma membrane that have been implicated in signal transduction and vesicular trafficking. Caveolins are a family of caveolae-associated integral membrane proteins (1). Caveolin, a 21- to 24-kDa integral membrane protein, is a principal component of caveolae membranes. Caveolin interacts directly with heterotrimeric guanine nucleotide binding proteins (G proteins) and can functionally regulate their activity. Caveolins 1 and 2 are similar in most respects, however, caveolin-1 and caveolin-2 differ in their functional interactions with heterotrimeric G proteins, possibly explaining why caveolin-1 and -2 are coexpressed within a single cell (2). Caveolin-2 is up-regulated in response to the mechanical injury of differentiated PC12 cells; up-regulation of caveolin-2 under these conditions is strictly dependent on continued treatment with NGF. Robust expression of caveolin-1 and -2 is also observed along the entire cell surface of DRG neurons, including high levels on growth cones. These findings demonstrate that neuronal cells express caveolins (1).

Alternate Names

CAV2, Caveolin2

Gene Symbol

CAV2

Additional Caveolin-2 Products

Product Documents for Caveolin-2 Antibody (8I4U7)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Caveolin-2 Antibody (8I4U7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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