CBP/KAT3A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-52906

Novus Biologicals, part of Bio-Techne
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NBP1-52906
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all CBP Antibodies »

Product Summary for CBP/KAT3A Antibody

Immunogen

Synthetic peptides corresponding to CREBBP(CREB binding protein (Rubinstein-Taybi syndrome)) The peptide sequence was selected from the N terminal of CREBBP (NP_001073315). Peptide sequence TPAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTHPGLLNSNS. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

261 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for CBP/KAT3A Antibody

Western Blot: CBP/KAT3A Antibody [NBP1-52906]

Western Blot: CBP/KAT3A Antibody [NBP1-52906]

Western Blot: CBP/KAT3A Antibody [NBP1-52906] - Jurkat cell lysate, concentration 1 ug/ml.
Immunohistochemistry: CBP/KAT3A Antibody [NBP1-52906]

Immunohistochemistry: CBP/KAT3A Antibody [NBP1-52906]

Immunohistochemistry: CBP/KAT3A Antibody [NBP1-52906] - Analysis of human breast after heat-induced Antigen retrieval. Antibody concentration 5 ug/ml.
Immunohistochemistry-Paraffin: CBP/KAT3A Antibody [NBP1-52906]

Immunohistochemistry-Paraffin: CBP/KAT3A Antibody [NBP1-52906]

Immunohistochemistry-Paraffin: CBP/KAT3A Antibody [NBP1-52906] - Human Colon Tissue, antibody concentration 5 ug/ml.

Applications for CBP/KAT3A Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CBP

CREBBP is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. CREBBP has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain.

Long Name

CREB-binding Protein

Alternate Names

CREBBP, RTS

Entrez Gene IDs

1387 (Human)

Gene Symbol

CREBBP

UniProt

Q92793

Additional CBP Products

Product Documents for CBP/KAT3A Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CBP/KAT3A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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