CBS Antibody (519)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-43604

Novus Biologicals, part of Bio-Techne
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NBP2-43604
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Key Product Details

Validated by

Knockout/Knockdown

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (94%), Rabbit (95%), Xenopus (93%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Knockdown Validated, Knockout Validated, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 519

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CBS Antibodies »

Product Summary for CBS Antibody (519)

Immunogen

Recombinant protein encompassing a sequence within the center region of human CBS. The exact sequence is proprietary.

Reactivity Notes

Xenopus laevis (93%).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

61 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CBS Antibody (519)

Knockout Validated: CBS Antibody (519) [NBP2-43604]

Knockout Validated: CBS Antibody (519) [NBP2-43604]

Knockout Validated: CBS Antibody (519) [NBP2-43604] - Wild-type (WT) and CBS knockout (KO) HeLa cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with CBS antibody [GT519]. HRP-conjugated anti-mouse IgG antibody was used to detect the primary antibody.
Knockdown Validated: CBS Antibody (519) [NBP2-43604]

Knockdown Validated: CBS Antibody (519) [NBP2-43604]

Knockdown Validated: CBS Antibody (519) [NBP2-43604] - Non-transfected (-) and transfected (+) 293T whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with CBS antibody [GT519].
Western Blot: CBS Antibody (519) [NBP2-43604]

Western Blot: CBS Antibody (519) [NBP2-43604]

Western Blot: CBS Antibody (519) [NBP2-43604] - Non-transfected (-) and transfected (+) 293T whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with CBS antibody (519) diluted at 1:1000. HRP-conjugated anti-mouse IgG antibody was used to detect the primary antibody.
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Applications for CBS Antibody (519)

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CBS

CBS is encoded by this gene is involved in the transsulfuration pathway. The first step of this pathway, from homocysteine to cystathionine, is catalyzed by this protein. CBS deficiency can cause homocystinuria which affects many organs and tissues, including the eyes and the skeletal, vascular and central nervous systems.

Alternate Names

cystathionine-beta-synthase, EC 4.2.1.2210Beta-thionase

Gene Symbol

CBS

Additional CBS Products

Product Documents for CBS Antibody (519)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CBS Antibody (519)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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