CBS Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83255

Novus Biologicals, part of Bio-Techne
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NBP1-83255
NBP1-83255-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CBS Antibodies »

Product Summary for CBS Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIGAPHR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

61 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CBS Antibody

Immunocytochemistry/ Immunofluorescence: CBS Antibody [NBP1-83255]

Immunocytochemistry/ Immunofluorescence: CBS Antibody [NBP1-83255]

Immunocytochemistry/Immunofluorescence: CBS Antibody [NBP1-83255] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoli & vesicles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: CBS Antibody [NBP1-83255]

Immunohistochemistry-Paraffin: CBS Antibody [NBP1-83255]

Immunohistochemistry-Paraffin: CBS Antibody [NBP1-83255] - Staining of human skeletal muscle shows no positivity in striated muscle fibers as expected.
Immunohistochemistry-Paraffin: CBS Antibody [NBP1-83255]

Immunohistochemistry-Paraffin: CBS Antibody [NBP1-83255]

Immunohistochemistry-Paraffin: CBS Antibody [NBP1-83255] - Staining of human liver shows moderate cytoplasmic positivity in hepatocytes.
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Applications for CBS Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CBS

CBS is encoded by this gene is involved in the transsulfuration pathway. The first step of this pathway, from homocysteine to cystathionine, is catalyzed by this protein. CBS deficiency can cause homocystinuria which affects many organs and tissues, including the eyes and the skeletal, vascular and central nervous systems.

Alternate Names

cystathionine-beta-synthase, EC 4.2.1.2210Beta-thionase

Entrez Gene IDs

875 (Human); 12411 (Mouse); 24250 (Rat)

Gene Symbol

CBS

UniProt

P35520 (Human)

Additional CBS Products

Product Documents for CBS Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CBS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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