CBX1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14899

Novus Biologicals, part of Bio-Techne
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NBP2-14899
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Chicken (96%), Xenopus (93%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CBX1 Antibodies »

Product Summary for CBX1 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human CBX1. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Zebrafish (83%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CBX1 Antibody

Western Blot: CBX1 Antibody [NBP2-14899]

Western Blot: CBX1 Antibody [NBP2-14899]

Western Blot: CBX1 Antibody [NBP2-14899] - Sample (30 ug of whole cell lysate) A: HeLa 12% SDS PAGE; antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: CBX1 Antibody [NBP2-14899]

Immunohistochemistry-Paraffin: CBX1 Antibody [NBP2-14899]

Immunohistochemistry-Paraffin: CBX1 Antibody [NBP2-14899] - CBX1 antibody detects CBX1 protein at nucleus in mouse brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse brain diluted at 1:500.
Immunohistochemistry-Paraffin: CBX1 Antibody [NBP2-14899]

Immunohistochemistry-Paraffin: CBX1 Antibody [NBP2-14899]

Immunohistochemistry-Paraffin: CBX1 Antibody [NBP2-14899] - Paraffin-embedded 59T xenograft, using antibody at 1:500 dilution.
View 1 more images

Applications for CBX1 Antibody

Application
Recommended Usage

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CBX1

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]

Alternate Names

CBXM31HP1-BETA, chromobox homolog 1, chromobox homolog 1 (Drosophila HP1 beta), chromobox homolog 1 (HP1 beta homolog Drosophila ), chromobox protein homolog 1, Heterochromatin protein 1 homolog beta, heterochromatin protein 1-beta, Heterochromatin protein p25, heterochromatin protein p25 beta, HP1 beta, HP1 beta homolog, HP1Hsbeta, HP1Hs-beta, MOD1, Modifier 1 protein, p25beta

Gene Symbol

CBX1

UniProt

P83916 (Human)

Additional CBX1 Products

Product Documents for CBX1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CBX1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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