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CCK-AR Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-2805

Novus Biologicals, part of Bio-Techne
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NB100-2805

Key Product Details

Species Reactivity

Human, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Peptide with sequence C-FEASQKKSAKERKPST corresponding to internal region according to NP_000721.1.

Reactivity Notes

Rat reactivity reported in (PMID: 19959964).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for CCK-AR Antibody

Immunohistochemistry-Paraffin: CCK-AR Antibody [NB100-2805]

Immunohistochemistry-Paraffin: CCK-AR Antibody [NB100-2805]

Immunohistochemistry-Paraffin: CCK-AR Antibody [NB100-2805] - Staining of paraffin embedded Human Pancreas. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining.

Applications for CCK-AR Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:10 - 1:500

Immunohistochemistry

2-4 ug/ml

Immunohistochemistry-Paraffin

2-4 ug/ml

Peptide ELISA

1:28000
Application Notes
ICC/IF successful usage for RIN-14B cells is reported in scientific literature (PMID: 19959964).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CCK-AR

CCKAR is a receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Long Name

Cholecystokinin Receptor, Type A

Alternate Names

CCK-A R, CCK1R, CCKAR

Entrez Gene IDs

886 (Human); 24889 (Rat)

Gene Symbol

CCKAR

UniProt

Additional CCK-AR Products

Product Documents for CCK-AR Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CCK-AR Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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