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CCNDBP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15762

Novus Biologicals, part of Bio-Techne
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NBP2-15762

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for CCNDBP1 Antibody

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CCNDBP1. The exact sequence is proprietary.

Localization

Cytoplasm; Nucleus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CCNDBP1 Antibody

Western Blot: CCNDBP1 Antibody [NBP2-15762]

Western Blot: CCNDBP1 Antibody [NBP2-15762]

Western Blot: CCNDBP1 Antibody [NBP2-15762] - Western Blot analysis of CCNDBP1 expression in transfected 293T cell line by CCNDBP1 polyclonal antibody. A: Non-transfected lysate. B: CCNDBP1 transfected lysate. 12% SDS PAGE gel, diluted at 1:500.
Immunohistochemistry-Paraffin: CCNDBP1 Antibody [NBP2-15762]

Immunohistochemistry-Paraffin: CCNDBP1 Antibody [NBP2-15762]

Immunohistochemistry-Paraffin: CCNDBP1 Antibody [NBP2-15762] - Immunohistochemical analysis of paraffin-embedded endo mitrial, using antibody at 1:100 dilution.

Applications for CCNDBP1 Antibody

Application
Recommended Usage

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CCNDBP1

This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Two alternatively spliced variants, which encode distinct isoforms, have been reported. [provided by RefSeq]

Alternate Names

cyclin D-type binding-protein 1, cyclin-D1-binding protein 1, DIP1HHM Protein, D-type cyclin-interacting protein 1, GCIPgrap2 cyclin interacting protein, Grap2 and cyclin-D-interacting protein, HHM, Human homolog of Maid, MAID protein

Gene Symbol

CCNDBP1

UniProt

Additional CCNDBP1 Products

Product Documents for CCNDBP1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CCNDBP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.