CCR2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB100-718

Novus Biologicals, part of Bio-Techne
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NB100-718-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all CCR2 Antibodies »

Product Specifications

Immunogen

Synthetic peptide C-G17EEVTTFFDYDYGAPCHKFDVKQ39 corresponding to the N-terminal extracellular domain of human CCR2.

Localization

Cell Membrane

Specificity

Peptide sequence is < 50 % identical to other human chemokine receptors in this region.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for CCR2 Antibody - BSA Free

Immunohistochemistry-Paraffin: CCR2 Antibody - BSA Free [NB100-718]

Immunohistochemistry-Paraffin: CCR2 Antibody - BSA Free [NB100-718]

Immunohistochemistry-Paraffin: CCR2 Antibody [NB100-718] - Section of human spleen.

Applications for CCR2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:30000

Immunohistochemistry

1:100

Immunohistochemistry-Paraffin

1:100

Western Blot

1:500

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

10mM KHPO4 and 0.14M NaCl

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CCR2

CCR2, or C C chemokine receptor type 2, is a receptor for several monocyte chemo attractant proteins (MCP1, MCP3, MCP4) which specifically mediate monocyte chemotaxis. CCR2 transduces such signals by increasing the intracellular level of calcium ions. For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. CCR2 is also an alternative coreceptor with CD4 for HIV1 infection. CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen and thymus.

Alternate Names

CC-CKR-2, CCR2, CCR2B, CD192, CKR2, CKR2A, CMKBR2, FLJ78302, MCP-1-R

Entrez Gene IDs

729230 (Human)

Gene Symbol

CCR2

Additional CCR2 Products

Product Documents for CCR2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CCR2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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