CCR3 Antibody (SR2050)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21677

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21677-100ul
NBP3-21677-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2050

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CCR3 Antibodies »

Product Summary for CCR3 Antibody (SR2050)

Immunogen

A synthesized peptide derived from human CCR3 (Uniprot #: P51677)

Specificity

Detects endogenous levels of total CCR3

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CCR3 Antibody (SR2050)

Western Blot: CCR3 Antibody (SR2050) [NBP3-21677] -

Western Blot: CCR3 Antibody (SR2050) [NBP3-21677] - Western blot analysis using NBP3-21677 in K562 cell lysate.

Immunohistochemistry: CCR3 Antibody (SR2050) [NBP3-21677] -

Immunohistochemistry: CCR3 Antibody (SR2050) [NBP3-21677] - Immunohistochemical analysis of paraffin-embedded human epidemal cells of skin, using NBP3-21677.

Applications for CCR3 Antibody (SR2050)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CCR3

CKR3, or C-C chemokine receptor type 3, is a G protein-coupled, seven-transmembrane domain receptor protein. The chemokine eotaxin appears to be a highly specific agonist for CKR3, making CKR3 one of the factors responsible for selective recruitment of eosinophils to sites of inflammation (1). It has been shown that more than one chemokine activates CKR3, including eotaxin, RANTES, and MCP-3 (2). Since CKR3 is prominently expressed in eosinophils , it has been named the human eosinophil eotaxin receptor (2,3).

Alternate Names

CCR3, CD193

Gene Symbol

CCR3

Additional CCR3 Products

Product Documents for CCR3 Antibody (SR2050)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CCR3 Antibody (SR2050)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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