CCR3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56335

Novus Biologicals, part of Bio-Techne
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NB100-56335
NB100-56335SS
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Azide Free
NB100-56545
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all CCR3 Antibodies »

Product Specifications

Immunogen

This antibody was raised against a synthetic peptide of human CCR3 protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CCR3 Antibody

Western Blot: CCR3 Antibody [NB100-56335]

Western Blot: CCR3 Antibody [NB100-56335]

Western Blot: CCR3 Antibody [NB100-56335] - Analysis using the Azide Free version of NB100-56335. Detection of 10 ug of total cell lysate from Daudi cells with this antibody at 2 ug/ml dilution.

Applications for CCR3 Antibody

Application
Recommended Usage

Western Blot

1-3 ug/ml
Application Notes
In Daudi, a 45 kDa band should be observed.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 0.2% gelatin

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CCR3

Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors (1). The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR3 (eotaxin receptor), is expressed on eosinophils and certain T cell population respond to a variety of CC chemokines apart from eotaxin, including RANTES, monocyte chemotactic protein (MCP)-2, MCP-3, and MCP-4 (2,3). CCR3 facilitated infection by a more restricted subset of primary viruses, and binding of the CCR3 ligand, eotaxin, and inhibited infection by these isolates (4).

Alternate Names

CCR3, CD193

Entrez Gene IDs

1232 (Human); 12771 (Mouse); 117027 (Rat)

Gene Symbol

CCR3

UniProt

NP_847899 (Human)

Additional CCR3 Products

Product Documents for CCR3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CCR3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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