CCR3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56335

Novus Biologicals, part of Bio-Techne
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NB100-56335
NB100-56335SS
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Azide Free
NB100-56545
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all CCR3 Antibodies »

Product Specifications

Immunogen

This antibody was raised against a synthetic peptide of human CCR3 protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CCR3 Antibody

Western Blot: CCR3 Antibody [NB100-56335]

Western Blot: CCR3 Antibody [NB100-56335]

Western Blot: CCR3 Antibody [NB100-56335] - Analysis using the Azide Free version of NB100-56335. Detection of 10 ug of total cell lysate from Daudi cells with this antibody at 2 ug/ml dilution.

Applications for CCR3 Antibody

Application
Recommended Usage

Western Blot

1-3 ug/ml
Application Notes
In Daudi, a 45 kDa band should be observed.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 0.2% gelatin

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CCR3

Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors (1). The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR3 (eotaxin receptor), is expressed on eosinophils and certain T cell population respond to a variety of CC chemokines apart from eotaxin, including RANTES, monocyte chemotactic protein (MCP)-2, MCP-3, and MCP-4 (2,3). CCR3 facilitated infection by a more restricted subset of primary viruses, and binding of the CCR3 ligand, eotaxin, and inhibited infection by these isolates (4).

Alternate Names

CCR3, CD193

Entrez Gene IDs

1232 (Human); 12771 (Mouse); 117027 (Rat)

Gene Symbol

CCR3

UniProt

NP_847899 (Human)

Additional CCR3 Products

Product Documents for CCR3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CCR3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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