CCR8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15767

Novus Biologicals, part of Bio-Techne
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NBP2-15767
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CCR8 Antibodies »

Product Summary for CCR8 Antibody

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CCR8. The exact sequence is proprietary.

Reactivity Notes

Bovine (85%).

Localization

Cell membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

41 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CCR8 Antibody

Immunohistochemistry-Paraffin: CCR8 Antibody [NBP2-15767]

Immunohistochemistry-Paraffin: CCR8 Antibody [NBP2-15767]

Immunohistochemistry-Paraffin: CCR8 Antibody [NBP2-15767] - CCR8 antibody detects CCR8 protein at cytosol and membrane on human hepatoma antibody dilution: 1:250. TrilogyTM (EDTA based) buffer, 15min
Immunohistochemistry-Paraffin: CCR8 Antibody [NBP2-15767]

Immunohistochemistry-Paraffin: CCR8 Antibody [NBP2-15767]

Immunohistochemistry-Paraffin: CCR8 Antibody [NBP2-15767] - Gastric carcinoma; antibody dilution: 1:500. Antigen Retrieval: TrilogyTM (EDTA based) buffer, 15min
CCR8 Antibody

Western Blot: CCR8 Antibody [NBP2-15767] -

Western Blot: CCR8 Antibody [NBP2-15767] -Various unboiled whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with CCR8 antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.

Applications for CCR8 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CCR8

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq]

Alternate Names

CCR8, CD198, CDw198, ChemR1, CKRL1, GPRCL1, TER-1

Gene Symbol

CCR8

UniProt

P51685

Additional CCR8 Products

Product Documents for CCR8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CCR8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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