CD1.1 antigen Antibody (CB3) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-28362

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Chicken

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # CB3

Format

Azide and BSA Free

Concentration

0.5 mg/ml

View all CD1.1 antigen Antibodies »

Product Specifications

Immunogen

Lymphocytes from the bursa of Fabricius of outbred chickens

Specificity

Chicken CD1.1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for CD1.1 antigen Antibody (CB3) - Azide and BSA Free

Flow Cytometry: CD1.1 antigen Antibody (CB3) - Azide and BSA Free [NBP1-28362]

Flow Cytometry: CD1.1 antigen Antibody (CB3) - Azide and BSA Free [NBP1-28362]

Flow Cytometry: CD1.1 antigen Antibody (CB3) [NBP1-28362] - Chicken peripheral blood mononuclear cells were stained with Mouse Anti-Chicken CD1.1-FITC and Mouse Anti-Chicken CD3-PE.
CD1.1 antigen Antibody (CB3) [NBP1-28362] - Chicken peripheral blood lymphocytes were stained with Mouse Anti-Chicken CD1.1-UNLB (SB Cat. No. 8430-01) followed by Goat Anti-Mouse IgG1, Human ads-PE (SB Cat. No. 1070-09).

Applications for CD1.1 antigen Antibody (CB3) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

<= 1 ug/10^6 cells

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.1M BBS (pH 8.2)

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: CD1.1 antigen

CD1 molecules, like MHC I and II, play an equally important role in the immune system by presenting lipid, glycolipid and lipopeptide antigen to T and NKT cells. (1) Chicken CD1 gene is located in the chicken MHC B locus and has an important implication for the primordial MHC gene evolution. (2) Two proteins have been identified: CD1.1 and CD1.2. Analysis of RNA from blood cells showed that both genes are expressed in Bu-1+ cells (B cells and some macrophages) and CD8a+ cells (some T and NK cells). CD1.2 is expressed in TCR1 + cells (gamma delta cells) but is nearly undetectable in TCR2+ and TCR3+ cells (alpha and Beta T cells)1. Clone CB3 antibody can identify cells of the B cell lineage and recognizes CD1.1 but not CD1.2 on the surface of transfected mammalian cells. (1)

Alternate Names

CD1, CD1a antigen, CD1A antigen, a polypeptide, CD1a molecule, cluster of differentiation 1 A, cortical thymocyte antigen CD1A, differentiation antigen CD1-alpha-3, epidermal dendritic cell marker CD1a, FCB6, HTA1, hTa1 thymocyte antigen, R4, T6, T-cell surface antigen T6/Leu-6, T-cell surface glycoprotein CD1a

Gene Symbol

CD1A

Additional CD1.1 antigen Products

Product Documents for CD1.1 antigen Antibody (CB3) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CD1.1 antigen Antibody (CB3) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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