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CD155/PVR Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88131

Novus Biologicals, part of Bio-Techne
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NBP1-88131
NBP1-88131-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CD155/PVR Antibody

Immunohistochemistry-Paraffin: CD155/PVR Antibody [NBP1-88131]

Immunohistochemistry-Paraffin: CD155/PVR Antibody [NBP1-88131]

Immunohistochemistry-Paraffin: CD155/PVR Antibody [NBP1-88131] - Analysis in human placenta and tonsil tissues. Corresponding PVR RNA-seq data are presented for the same tissues.
Western Blot: CD155/PVR Antibody [NBP1-88131]

Western Blot: CD155/PVR Antibody [NBP1-88131]

Western Blot: CD155/PVR Antibody [NBP1-88131] - Analysis in human cell lines A-431 and MCF-7 using Anti-PVR antibody. Corresponding PVR RNA-seq data are presented for the same cell lines. Loading control: Anti-GAPDH.
Immunohistochemistry-Paraffin: CD155/PVR Antibody [NBP1-88131]

Immunohistochemistry-Paraffin: CD155/PVR Antibody [NBP1-88131]

Immunohistochemistry-Paraffin: CD155/PVR Antibody [NBP1-88131] - Staining of human tonsil shows no positivity in lymphoid cells as expected.

Applications for CD155/PVR Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04 - 0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD155/PVR

Polio Virus Receptor (PVR) is a member of Ig-superfamily with 3 Ig-domains in arrangement V-C-C. Four mRNAs are produced from single gene for PVR, (mapped to human chromosome band 19q13.1-13.2). Two of the mRNAs (called H20A and H20B or alpha and delta) encode cell surface molecules of about 43kDa and 45kDa polypeptide backbone, respectively. Two other splice variants, beta and gamma encode secreted molecules of about 44kDa. The cytoplasmic tails are short (aa 35-50) and are rich in serine phosphorylated residues.

Long Name

Poliovirus Receptor

Alternate Names

CD155, HVED, Necl-5, PVR, PVS

Gene Symbol

PVR

Additional CD155/PVR Products

Product Documents for CD155/PVR Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD155/PVR Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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