CD1c/BDCA-1 Antibody (L161)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-62220

Clone L161 was used by HLDA to establish CD designation.
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow (Cell Surface), Flow Cytometry, Immunohistochemistry, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # L161

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CD1c/BDCA-1 Antibodies »

Product Summary for CD1c/BDCA-1 Antibody (L161)

Immunogen

human thymocytes

Specificity

The antibody MEM-97 reacts with CD20 (Bp35), a 33-37 kDa non-glycosylated membrane receptor with four transmembrane domains, expressed on B lymphocytes (it is lost on plasma cells), follicular dendritic cells, and at low levels on peripheral blood T lymphocytes.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Theoretical MW

43 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CD1c/BDCA-1 Antibody (L161)

Flow Cytometry: CD1c/BDCA-1 Antibody (L161) [NBP2-62220]

Flow Cytometry: CD1c/BDCA-1 Antibody (L161) [NBP2-62220]

Flow Cytometry: CD1c/BDCA-1 Antibody (L161) [NBP2-62220] - Separation of human CD1c positive CD19 positive lymphocytes (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood using anti-human CD1c (L161) purified antibody (concentration in sample 0,33 ug/ml, GAM APC).
Flow Cytometry: CD1c/BDCA-1 Antibody (L161) [NBP2-62220]

Flow Cytometry: CD1c/BDCA-1 Antibody (L161) [NBP2-62220]

Flow Cytometry: CD1c/BDCA-1 Antibody (L161) [NBP2-62220] - Surface staining of human peripheral blood cells with anti-human CD1c (clone L161) PE.
Flow (Cell Surface): CD1c/BDCA-1 Antibody (L161) [NBP2-62220]

Flow (Cell Surface): CD1c/BDCA-1 Antibody (L161) [NBP2-62220]

Flow (Cell Surface): CD1c/BDCA-1 Antibody (L161) [NBP2-62220] - Surface staining pattern of human peripheral whole blood stained using anti-human CD1c (L161) purified antibody (concentration in sample 0,33 ug/ml, GAM APC).
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Applications for CD1c/BDCA-1 Antibody (L161)

Application
Recommended Usage

Flow Cytometry

1-4 ug/ml

Immunohistochemistry

1:10-1:500

Immunoprecipitation

1:10-1:500
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

0.9% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: CD1c/BDCA-1

All CD1 molecules, except CD1e, are cell surface glycoproteins that are structurally related to the MHC molecules, however, in distinction, CD1 proteins are essentially non polymorphic. CD1 has considerable structural homology with both MHC class I and class II molecules, and CD1 molecules are involved in T cell activation. In contrast to MHC, however, CD1 molecules appear to present predominantly non peptide molecules originating from lipids and glycolipids.

Alternate Names

BDCA-1, BDCA1, CD1c, R7

Gene Symbol

CD1C

Additional CD1c/BDCA-1 Products

Product Documents for CD1c/BDCA-1 Antibody (L161)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CD1c/BDCA-1 Antibody (L161)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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