CD200R4 Antibody (4) [Janelia Fluor® 669]
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-90661JF669
Key Product Details
Species Reactivity
Applications
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Antibody Source
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Product Specifications
Immunogen
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Applications for CD200R4 Antibody (4) [Janelia Fluor® 669]
ELISA
Formulation, Preparation, and Storage
Purification
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Preservative
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Shipping
Stability & Storage
Background: CD200R4
CD200 antigen, also known as OX-2, is a type I transmembrane protein belonging to the Ig superfamily. It has a 202 amino acid extracellular domain and a short (19 aa) cytoplasmic tail. At least two alternate splice isoforms exist that differ in their cytoplasmic domains. CD200 is widely expressed in multiple cell types. It interacts with CD200 R1, another Ig superfamily inhibitory receptor primarily expressed on leukocytes of the myeloid lineage, to inhibit myeloid functions.
CD200 R1, also known as OX-2 receptor, is a transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed primarily in cells of the myeloid lineage, while its ligand, CD200, is widely distributed. CD200 R1 is though to propagate inhibitory signals and disruption of the CD200/CD200 R1 receptor-ligand pair leads to a predisposition to autoimmune phenotypes.
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Additional CD200R4 Products
Product Documents for CD200R4 Antibody (4) [Janelia Fluor® 669]
Product Specific Notices for CD200R4 Antibody (4) [Janelia Fluor® 669]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.