CD23/Fc epsilon RII Antibody (EBVCS2) [DyLight 405]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-43433V

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Product Datasheet / COA / SDS

View Available Conjugates

Conjugate

Catalog #

Unconjugated

NBP1-43433

Alexa Fluor 350

NBP1-43433AF350

Alexa Fluor 405

NBP1-43433AF405

Alexa Fluor 488

NBP1-43433AF488

Alexa Fluor 532

NBP1-43433AF532

Alexa Fluor 594

NBP1-43433AF594

Alexa Fluor 647

NBP1-43433AF647

Alexa Fluor 700

NBP1-43433AF700

Alexa Fluor 750

NBP1-43433AF750

Allophycocyanin

NBP1-43433APC

Allophycocyanin/Cy7

NBP1-43433APCCY7

Biotin

NBP1-43433B

CoraFluor 1

NBP1-43433CL1

DyLight 350

NBP1-43433UV

DyLight 488

NBP1-43433G

DyLight 550

NBP1-43433R

DyLight 594

NBP1-43433DL594

DyLight 650

NBP1-43433C

DyLight 680

NBP1-43433FR

DyLight 755

NBP1-43433IR

FITC

NBP1-43433F

HRP

NBP1-43433H

Janelia Fluor 525

NBP1-43433JF525

Janelia Fluor 549

NBP1-43433JF549

Janelia Fluor 585

NBP1-43433JF585

Janelia Fluor 635

NBP1-43433JF635

Janelia Fluor 646

NBP1-43433JF646

Janelia Fluor 669

NBP1-43433JF669

mFluor Violet 450 SE

NBP1-43433MFV450

mFluor Violet 500 SE

NBP1-43433MFV500

mFluor Violet 610 SE

NBP1-43433MFV610

PE

NBP1-43433PE

PE

NBP1-43882

PE/Atto594

NBP1-43433PEATT594

PE/Cy5.5

NBP1-43433PECY55

PE/Cy7

NBP1-42966

PE/Cy7

NBP1-43433PECY7

PerCP

NBP1-43433PCP

PerCP/Cy5.5

NBP1-42855

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Monoclonal Mouse IgG₁ Clone # EBVCS2

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CD23/Fc epsilon RII Antibodies »

Product Summary for CD23/Fc epsilon RII Antibody (EBVCS2) [DyLight 405]

Immunogen

The immunogen for this antibody was CD23.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for CD23/Fc epsilon RII Antibody (EBVCS2) [DyLight 405]

Application

Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CD23/Fc epsilon RII

The CD23 antigen is the low affinity IgE Fc receptor, which is a 49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells), and can also be found on the surface of T cells, macrophages, platelets and EBV transformed B lymphoblasts. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic Lymphocytic leukemia. CD23 is expressed by B cells in the follicular mantle but not by proliferating germinal centre cells. CD23 is also expressed by eosinophils. CD23 is distinct from the high affinity IgE receptors found on basophils and mast cells, which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface expression appears to be integral with the complex IgE system, which involves interactions of cells, cytokines, antibodies and regulatory factors. CD23 has been described as a

Long Name

Fc epsilon Receptor II

Alternate Names

CD23, CLEC4J, Fc epsilon RII, FCER2, Fcer2a, FceRII, IGEBF, Ly-42

Gene Symbol

FCER2

Additional CD23/Fc epsilon RII Products

Product Documents for CD23/Fc epsilon RII Antibody (EBVCS2) [DyLight 405]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for CD23/Fc epsilon RII Antibody (EBVCS2) [DyLight 405]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

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Flow Cytometry