Key Product Details

Species Reactivity

Mouse

Applications

Block/Neutralize, CyTOF-ready, Flow Cytometry, Immunoprecipitation, Inhibition of T Cell Function

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2 Clone # AP-MAB0825

Format

Azide and BSA Free

Concentration

1.0 mg/ml

View all CD27 Ligand/TNFSF7 Antibodies »

Product Specifications

Immunogen

Mouse B lymphoma

Clonality

Monoclonal

Host

Rat

Isotype

IgG2

Applications for CD27 Ligand/TNFSF7/CD70 Antibody (AP-MAB0825) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Immunoprecipitation

1:10-1:500
Application Notes
Flow Cytometry, Immunoprecipitation, Blocking of CD70-CD27 binding in vitro and Inhibiting T and NK cell responses. This antibody is CyTOF ready.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CD27 Ligand/TNFSF7

CD70 is a type II transmembrane protein. It is a member of the TNF superfamily, expressed on activated B cells, activated dendritic cells, and some activated T cells (low levels). CD70 interacts with CD27 to promote T-B cell cross-stimulation and co-stimulate B cell proliferation and immunoglobulin production. Cells expressing CD70 can co-stimulate T cell proliferation and enhance the production of cytokines.

Alternate Names

CD70, TNFSF7

Entrez Gene IDs

21948 (Mouse)

Gene Symbol

CD70

Additional CD27 Ligand/TNFSF7 Products

Product Documents for CD27 Ligand/TNFSF7/CD70 Antibody (AP-MAB0825) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CD27 Ligand/TNFSF7/CD70 Antibody (AP-MAB0825) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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