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CD35 Antibody (CR1/4382R)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-07753

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # CR1/4382R

Concentration

0.2 mg/ml

Product Specifications

Immunogen

Synthetic peptide corresponding to CD35 residues within aa1939-2039 of CD35 was used as an immunogen. (Uniprot: P17927 )

Localization

Cell surface

Marker

Follicular Dendritic Cell Marker

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

224 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-08296)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.

Scientific Data Images for CD35 Antibody (CR1/4382R)

Immunohistochemistry-Paraffin: CD35 Antibody (CR1/4382R) [NBP3-07753]

Immunohistochemistry-Paraffin: CD35 Antibody (CR1/4382R) [NBP3-07753]

Immunohistochemistry-Paraffin: CD35 Antibody (CR1/4382R) [NBP3-07753] - Formalin-fixed, paraffin-embedded human tonsil stained with CD35 Recombinant Rabbit Monoclonal Antibody (CR1/4382R).
Immunohistochemistry-Paraffin: CD35 Antibody (CR1/4382R) [NBP3-07753]

Immunohistochemistry-Paraffin: CD35 Antibody (CR1/4382R) [NBP3-07753]

Immunohistochemistry-Paraffin: CD35 Antibody (CR1/4382R) [NBP3-07753] - Formalin-fixed, paraffin-embedded human tonsil stained with CD35 Recombinant Rabbit Monoclonal Antibody (CR1/4382R).

Applications for CD35 Antibody (CR1/4382R)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: CD35

CD35 encodes a membrane glycoprotein found on peripheral blood cells, glomerular podocytes, and follicular dendritic cells. The protein is a receptor for complement components C3b and C4b and regulates the activity of the complement cascade. Variation in this protein is the basis of the Knops blood group system. The two most common alleles, F and S, differ by 8 exons and are thought to be the result of an unequal crossover event. A secreted form of the protein present in plasma has been described, but its full length nature has not been determined.

Alternate Names

C3BR, CD35, CR1, KN

Gene Symbol

CR1

UniProt

Additional CD35 Products

Product Documents for CD35 Antibody (CR1/4382R)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD35 Antibody (CR1/4382R)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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