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CD37 Antibody (MB-1) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11967

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-11967-0.025mg
NBP3-11967-0.2mg

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Mouse IgG1 kappa Clone # MB-1

Format

Azide and BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

BALB/c mice were immunized with lymph node cells from a patient with nodular poorly differentiated lymphocytic lymphoma. Immunophenotyping studies of these cells identified them as B cells expressing SIgG/lambda, as well as HLA-DR. Leu-12, and B1.

Specificity

This antibody is specific for human CD37, which is expressed on virtually all mature B lymphocytes, but not on pro-B or plasma cells. CD37 is highly expressed on all forms of B cell non-Hodgkin lymphoma, chronic lymphocyte leukemia, and other leukemias. CD37 does not appear to be expressed on T cells, thymocytes, granulocytes or platelets.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for CD37 Antibody (MB-1) - Azide and BSA Free

Immunocytochemistry/ Immunofluorescence: CD37 Antibody (MB-1) - Azide and BSA Free [NBP3-11967]

Immunocytochemistry/ Immunofluorescence: CD37 Antibody (MB-1) - Azide and BSA Free [NBP3-11967]

Immunocytochemistry/Immunofluorescence: CD37 Antibody (MB-1) [NBP3-11967] - Immunofluorescence analysis of paraformaldehyde fixed Daudi cells stained with the chimeric mouse IgG version of OX-126 (NBP3-11967) at 10 ug/ml followed by Alexa Fluor(R) 488 secondary antibody (2 ug/ml), showing membrane staining. The nuclear stain is DAPI (blue). Panels show from left-right, top-bottom NBP3-11967, DAPI, merged channels and an isotype control. The isotype control was stained with anti-unknown antibody followed by Alexa Fluor(R) 488 secondary antibody.

Applications for CD37 Antibody (MB-1) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

0.02% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.

Background: CD37

CD37, also known as GP52-40, TSPAN26, MGC120234. Enterz Protein NP_001035120. It is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.

Alternate Names

CD37, TSPAN26

Gene Symbol

CD37

Additional CD37 Products

Product Documents for CD37 Antibody (MB-1) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD37 Antibody (MB-1) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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