CD42b/GPIb alpha Antibody (1C6)

Novus Biologicals, part of Bio-Techne | Catalog # H00002811-M02

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 1C6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CD42b/GPIb alpha Antibodies »

Product Specifications

Immunogen

GP1BA (AAH27955, 19 a.a. ~ 128 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. ICEVSKVASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVPFNRL

Specificity

glycoprotein Ib (platelet), alpha polypeptide

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for CD42b/GPIb alpha Antibody (1C6)

Immunoprecipitation: CD42b/GPIb alpha Antibody (1C6) [H00002811-M02]

Immunoprecipitation: CD42b/GPIb alpha Antibody (1C6) [H00002811-M02]

Immunoprecipitation: CD42b/GPIb alpha Antibody (1C6) [H00002811-M02] - Analysis of GP1BA transfected lysate using anti-GP1BA monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with GP1BA MaxPab rabbit polyclonal antibody.
ELISA: CD42b/GPIb alpha Antibody (1C6) [H00002811-M02]

ELISA: CD42b/GPIb alpha Antibody (1C6) [H00002811-M02]

ELISA: CD42b/GPIb alpha Antibody (1C6) [H00002811-M02] - Detection limit for recombinant GST tagged GP1BA is approximately 0.03ng/ml as a capture antibody.

Applications for CD42b/GPIb alpha Antibody (1C6)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CD42b/GPIb alpha

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease.

Long Name

Glycoprotein lb [Platelet] alpha

Alternate Names

BP1BA, BSS, CD42b, GP1BA, GPIb alpha

Entrez Gene IDs

2811 (Human)

Gene Symbol

GP1BA

OMIM

177820 (Human)

UniProt

AAH27955 (Human)

Additional CD42b/GPIb alpha Products

Product Documents for CD42b/GPIb alpha Antibody (1C6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CD42b/GPIb alpha Antibody (1C6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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