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CD45RA Antibody (CA4.1D3)

Novus Biologicals, part of Bio-Techne | Catalog # NB100-64897

Novus Biologicals, part of Bio-Techne
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NB100-64897
NB100-64897-0.25ml

Key Product Details

Species Reactivity

Canine

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CA4.1D3

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Product Specifications

Immunogen

Made to Dog CD45RA

Specificity

Recognizes the canine homologue of CD45RA, a cell surface glycoprotein expressed by B lymphocytes and a subset of T-lymphocytes.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for CD45RA Antibody (CA4.1D3)

Flow Cytometry: CD45RA Antibody (CA4.1D3) [NB100-64897]

Flow Cytometry: CD45RA Antibody (CA4.1D3) [NB100-64897]

Flow Cytometry: CD45RA Antibody (CA4.1D3) [NB100-64897] - Pan leukocyte detection in Canine IP- whole blood cells. Image courtesy of customer.

Applications for CD45RA Antibody (CA4.1D3)

Application
Recommended Usage

Flow Cytometry

Neat

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500

Reviewed Applications

Read 1 review rated 5 using NB100-64897 in the following applications:

Formulation, Preparation, and Storage

Purification

Tissue culture supernatant

Formulation

Tissue culture supernatant

Preservative

0.01% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD45RA

CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220, 205, 190, 180 kDa) which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognizing a common epitope on all of the isoforms are termed CD45 whilst those recognizing only individual isoforms are termed CD45RA or CD45RO etc.

Long Name

CD45R, A isoform

Alternate Names

B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide

Gene Symbol

PTPRC

Additional CD45RA Products

Product Documents for CD45RA Antibody (CA4.1D3)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD45RA Antibody (CA4.1D3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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