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CD47 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-32031

Novus Biologicals, part of Bio-Techne
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NBP2-32031
NBP2-32031-25ul

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: AQLLFNKTKSVEFTFCNDTVVIPCFVTNMEAQNTTEVYVKWKFKGRDIYTFDGALNKSTVPTDFSSAKIEVSQLLKGDASLKMDKSDAVSHTGNYTCEVTELTREGETIIELKYRVVS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CD47 Antibody

Immunohistochemistry-Paraffin: CD47 Antibody [NBP2-32031]

Immunohistochemistry-Paraffin: CD47 Antibody [NBP2-32031]

Immunohistochemistry-Paraffin: CD47 Antibody [NBP2-32031] - Staining of human fallopian tube shows moderate to strong membranous positivity in glandular cells.
Immunohistochemistry-Paraffin: CD47 Antibody [NBP2-32031]

Immunohistochemistry-Paraffin: CD47 Antibody [NBP2-32031]

Immunohistochemistry-Paraffin: CD47 Antibody [NBP2-32031] - Staining of human prostate shows moderate membranous positivity in glandular cells.
Immunohistochemistry-Paraffin: CD47 Antibody [NBP2-32031]

Immunohistochemistry-Paraffin: CD47 Antibody [NBP2-32031]

Immunohistochemistry-Paraffin: CD47 Antibody [NBP2-32031] - Staining of human tonsil shows moderate membranous positivity in non - germinal center cells.

Applications for CD47 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reviewed Applications

Read 1 review rated 5 using NBP2-32031 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD47

CD47 antigen, also known as integrin associated protein (IAP), has a very broad tissue distribution. CD47 is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. There are approximately 50.000 CD47 molecules per erythrocyte. The glycoprotein is deficient in erythrocytes of the rare Rh null phenotype. CD47 is a heavily N glycosylated cell membrane glycoprotein of apparent molecular weight 47-52 kDa. It may play a role as a signaltransducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells.

Alternate Names

CD47, IAP, MER6, OA3

Gene Symbol

CD47

UniProt

Additional CD47 Products

Product Documents for CD47 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD47 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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