CD69 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-37926

Novus Biologicals, part of Bio-Techne
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NBP2-37926
NBP2-37926-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CD69 Antibodies »

Product Summary for CD69 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: VGQYNCPGQYTFSMPSDSHVSSCSEDWVGYQRKCYFISTVKRSWTSAQNACSEHGATLAVIDSE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CD69 Antibody

Immunohistochemistry-Paraffin: CD69 Antibody [NBP2-37926]

Immunohistochemistry-Paraffin: CD69 Antibody [NBP2-37926]

Immunohistochemistry-Paraffin: CD69 Antibody [NBP2-37926] - Staining of human lymph node shows moderate membranous positivity in germinal center cells.
Immunohistochemistry-Paraffin: CD69 Antibody [NBP2-37926]

Immunohistochemistry-Paraffin: CD69 Antibody [NBP2-37926]

Immunohistochemistry-Paraffin: CD69 Antibody [NBP2-37926] - Staining of human duodenum shows moderate membranous positivity in a subset of lymphoid cells.
Immunohistochemistry-Paraffin: CD69 Antibody [NBP2-37926]

Immunohistochemistry-Paraffin: CD69 Antibody [NBP2-37926]

Immunohistochemistry-Paraffin: CD69 Antibody [NBP2-37926] - Staining of human pancreas shows no positivity in exocrine and endocrine glandular cells as expected.
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Applications for CD69 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD69

CD69, also known as very early activation (VEA) antigen, is a disulfide-linked transmembrane homodimer whose differentially glycosylated subunits range from 35-39 kDa. (1,2) It is a C-type lectin, most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules. (3) CD69 is widely expressed on hematopoietic cells, including lymphocytes, neutrophils and eosinophils. (1-4) Although not detectable on resting lymphocytes, its expression is rapidly (within 2 hours) upregulated upon activation of T, B and NK cells, and neutrophils. (4) Constitutive expression of CD69 on subsets of thymocytes suggests that it may be involved in regulation of developmental events in addition to its role in activation of a variety of hematopoietic cells. (4,5) MAb H1.2F3 augments PMA-induced T-cell proliferation,1,6 and induces redirected lysis of Fc receptor-bearing target cells by NK cells. (7)

Alternate Names

CD69, EA-1, Leu23, MLR-3, p60

Gene Symbol

CD69

UniProt

Q07108

Additional CD69 Products

Product Documents for CD69 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CD69 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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