CD72.1 Antibody (10-1.D.2) [FITC]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-28023

Novus Biologicals, part of Bio-Techne
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NBP1-28023
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Biotin
NBP1-28024
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Key Product Details

Species Reactivity

Mouse

Applications

Flow Cytometry

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 10-1.D.2

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CD72.1 Antibodies »

Product Specifications

Immunogen

DBA/2 mouse spleen cells

Reactivity Notes

Mouse. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Specificity

Mouse CD72.1/Lyb-2.1, 45 kDa

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for CD72.1 Antibody (10-1.D.2) [FITC]

Flow Cytometry: CD72.1 Antibody (10-1.D.2) [FITC] [NBP1-28023] - BALB/c spleen cells were double-stained with mouse anti-mouse CD72.1-FITC and rat anti-mouse CD19-RPE. Lymphocytes were then gated and analyzed by flow cytometry.

Applications for CD72.1 Antibody (10-1.D.2) [FITC]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: CD72.1

Murine CD72.1/Lyb-2.1, a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 (Ly-1) which is distributed on all T cells and a small number of B cells. (1,2) The 10-1.D.2 monoclonal antibody blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. (1) However, 10-1.D.2 can itself trigger a positive signal by binding CD72.1-5

Alternate Names

CD72 antigen, Ly19, Ly32, Lyb2, Lym19

Gene Symbol

Cd72

Additional CD72.1 Products

Product Documents for CD72.1 Antibody (10-1.D.2) [FITC]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CD72.1 Antibody (10-1.D.2) [FITC]

Conjugated forms should be protected from prolonged exposure to light.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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