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CD8 beta Antibody (341) - Low Endotoxin and Azide Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-05298

Novus Biologicals, part of Bio-Techne
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NBP3-05298-0.1mg

Key Product Details

Species Reactivity

Validated:

Rat

Applications

Flow Cytometry, Functional, Immunohistochemistry-Frozen, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse Clone # 341

Format

Low Endotoxin and Azide Free

Concentration

1 mg/ml

Product Summary for CD8 beta Antibody (341) - Low Endotoxin and Azide Free

Immunogen

CD8 positive Wistar rat splenic T cell hybridomas

Specificity

The mouse monoclonal antibody 341 (also known as 34.1) recognizes rat CD8b, the 32-34 kDa beta chain of the CD8 coreceptor (extracellular epitope), expressed on T cell subsets and some other cell types, such as macrophages.

Clonality

Monoclonal

Host

Mouse

Scientific Data Images for CD8 beta Antibody (341) - Low Endotoxin and Azide Free

Flow Cytometry: CD8 beta Antibody (341) - Low Endotoxin and Azide Free [NBP3-05298]

Flow Cytometry: CD8 beta Antibody (341) - Low Endotoxin and Azide Free [NBP3-05298]

Flow Cytometry: CD8 beta Antibody (341) - Low Endotoxin and Azide Free [NBP3-05298] - Separation of murine CD8b positive cells (red-filled) from CD8b negative cells (black-dashed) in flow cytometry analysis (surface staining) of murine splenocyte suspension stained using anti-rat CD8b (341) purified antibody (concentration in sample 1 ug/ml, GAM APC).
Flow Cytometry: CD8 beta Antibody (341) - Low Endotoxin and Azide Free [NBP3-05298]

Flow Cytometry: CD8 beta Antibody (341) - Low Endotoxin and Azide Free [NBP3-05298]

Flow Cytometry: CD8 beta Antibody (341) - Low Endotoxin and Azide Free [NBP3-05298] - Surface staining pattern of rat splenocyte suspension stained using anti-rat CD8b (341) purified antibody (concentration in sample 1 ug/ml, GAM APC).

Applications for CD8 beta Antibody (341) - Low Endotoxin and Azide Free

Application
Recommended Usage

Flow Cytometry

1-4 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

Phosphate buffered saline (PBS), pH 7.4

Format

Low Endotoxin and Azide Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: CD8 beta

The H35-17.2 monoclonal antibody reacts with the mouse CD8beta molecule. The CD8beta chain associates with the CD8alpha chain to form the CD8alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alphabeta TCR T cells. CD8 binds to MHC class I and plays a role in T cell development and activation of mature T cells.

Alternate Names

CD8 beta, CD8b, CD8B1, Leu2, LY3, LYT3, P37

Gene Symbol

CD8B

Additional CD8 beta Products

Product Documents for CD8 beta Antibody (341) - Low Endotoxin and Azide Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD8 beta Antibody (341) - Low Endotoxin and Azide Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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