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CD96 Antibody (NK92.39)

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-51137

Novus Biologicals, part of Bio-Techne
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NBP1-51137

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # NK92.39

Concentration

0.1 mg/ml

Product Specifications

Immunogen

The immunogen for this antibody is proprietary information.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for CD96 Antibody (NK92.39)

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.2 um filtered solution in PBS and 0.1% BSA

Preservative

No Preservative

Concentration

0.1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: CD96

The monoclonal antibody NK92.39 reacts with CD96, also known as T cell-activated increased late expression (Tactile). CD96 promotes natural killer (NK) cell adhesion to target cells expressing the poliovirus receptor (PVR or CD155). Furthermore CD96 stimulates cytotoxicity of activated NK cells, and mediates acquisition of PVR from target cells. This means NK cells have due to the receptor CD96 a dual receptor system that recognizes nectins and nectin-like molecules on target cells and mediates NK cells adhesion and triggering of effector functions. As PVR is highly expressed in certain tumors, this receptor system may be critical for NK cell recognition of tumors. The monoclonal antibody NK92.39 blocks binding of soluble poliovirus receptor (PVR) to NK92 cells.

Alternate Names

CD96, TACTILE

Gene Symbol

CD96

Additional CD96 Products

Product Documents for CD96 Antibody (NK92.39)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD96 Antibody (NK92.39)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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