CDC37 [p Ser13] Antibody (3B3)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26429

Recombinant monoclonal antibody expressed in HEK293F cells
Novus Biologicals, part of Bio-Techne
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NBP3-26429-100ul
NBP3-26429-50ul
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 3B3

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CDC37 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from Human CDC37 [p Ser13] [UniProt Q16543]

Modification

p Ser 13

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CDC37 [p Ser13] Antibody (3B3)

CDC37 [p Ser13] Antibody (3B3)

Western Blot: CDC37 [p Ser13] Antibody (3B3) [NBP3-26429] -

Western Blot: CDC37 [p Ser13] Antibody (3B3) [NBP3-26429] - Positive Western Blot detected in Hela whole cell lysate.
All lanes: CDC37 [p Ser13] Antibody at 0.6ug/ml.
Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution.
Predicted band size: 50 KDa
Observed band size: 50 KDa

Applications for CDC37 [p Ser13] Antibody (3B3)

Application
Recommended Usage

Western Blot

1:500-1:5000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl and 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: CDC37

In S. cerevisiae, Cdc37 has been shown to be an important regulator of cell division cycle through its action on cyclin-dependent kinases (CDK's). Cdc37 has also been associated with signaling pathways and kinases unrelated to cell cycle control, including v-Src, casein kinase II, MPS1 kinase and the sevenless receptor tyrosine kinase. Interestingly, HSP90 has also been shown to be associated with many of the same cellular targets as Cdc37. It has now been shown that Cdc37 is the same protein previously described as p50 which has been found to be associated with many of the same proteins as HSP90. Among others, Cdc37/p50 has been found complexed with Src-family kinases (Fyn, Yes, Fes, Lck & Fgr), Raf and pp60v-src. More recently, Cdc37 has been shown to be a chaperone independently and in concert with HSP90. In fact, Cdc37 is necessary for the binding of HSP90 to Cdk4.

Alternate Names

CDC37 (cell division cycle 37, S. cerevisiae, homolog), CDC37 cell division cycle 37 homolog, CDC37 cell division cycle 37 homolog (S. cerevisiae), CDC37A, cell division cycle 37 homolog (S. cerevisiae), Hsp90 chaperone protein kinase-targeting subunit, hsp90 co-chaperone Cdc37, p50Cdc37

Gene Symbol

CDC37

Additional CDC37 Products

Product Documents for CDC37 [p Ser13] Antibody (3B3)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CDC37 [p Ser13] Antibody (3B3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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