CDK2 [p Tyr15] Antibody (SR1560)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21552

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21552-50ul
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1560

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CDK2 Antibodies »

Product Summary for CDK2 [p Tyr15] Antibody (SR1560)

Immunogen

A synthesized peptide derived from human phospho-CDK2 [Tyr15] (Uniprot #: P24941)

Modification

p Tyr15

Specificity

Detects endogenous levels of phospho-CDK2 [Tyr15]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

34 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CDK2 [p Tyr15] Antibody (SR1560)

Western Blot: CDK2 [p Tyr 15] Antibody (SR1560) [NBP3-21552] -

Western Blot: CDK2 [p Tyr 15] Antibody (SR1560) [NBP3-21552] - Western blot analysis using NBP3-21552 in (1) HeLa treated with AP; (2) HeLa cell lysate.

Immunohistochemistry: CDK2 [p Tyr 15] Antibody (SR1560) [NBP3-21552] -

Immunohistochemistry: CDK2 [p Tyr 15] Antibody (SR1560) [NBP3-21552] - Immunohistochemical analysis of paraffin-embedded human bladder cancer, using NBP3-21552.

Applications for CDK2 [p Tyr15] Antibody (SR1560)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Immunohistochemistry-Paraffin

1:50-1:200

Immunoprecipitation

1:50

Western Blot

1:1000-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CDK2

The protein encoded by the Cdk2 gene is a member of the Ser/Thr protein kinase family. This protein kinase is highlysimilar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of thecyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycleG1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex includingcyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its proteinphosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have beenreported. (provided by RefSeq)

Long Name

Cyclin-dependent Kinase 2

Alternate Names

cdc2-related protein kinase, cell devision kinase 2, Cell division protein kinase 2, cyclin-dependent kinase 2, EC 2.7.11, EC 2.7.11.22, p33 protein kinase, p33(CDK2)

Gene Symbol

CDK2

Additional CDK2 Products

Product Documents for CDK2 [p Tyr15] Antibody (SR1560)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CDK2 [p Tyr15] Antibody (SR1560)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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