CDNF Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76834

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Rat

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Frozen, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all CDNF Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 9 amino acid synthetic peptide from near the carboxy terminus of human CDNF. The immunogen is located within the last 50 amino acids of CDNF. Amino Acid Squence: YAATHPKTE

Specificity

This antibody does not cross-react with MANF.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CDNF Antibody - BSA Free

Western Blot: CDNF AntibodyBSA Free [NBP1-76834]

Western Blot: CDNF AntibodyBSA Free [NBP1-76834]

Western Blot: CDNF Antibody [NBP1-76834] - Mouse brain tissue lysate with CDNF antibody at (A) 2 and (B) 4 ug/ml.
Immunocytochemistry/ Immunofluorescence: CDNF Antibody - BSA Free [NBP1-76834]

Immunocytochemistry/ Immunofluorescence: CDNF Antibody - BSA Free [NBP1-76834]

Immunocytochemistry/Immunofluorescence: CDNF Antibody - BSA Free [NBP1-76834] - CDNF Antibody [NBP1-76834] - Staining of CDNF in mouse brain tissue with at 20 ug/mL.
Immunohistochemistry-Paraffin: CDNF Antibody - BSA Free [NBP1-76834]

Immunohistochemistry-Paraffin: CDNF Antibody - BSA Free [NBP1-76834]

Immunohistochemistry-Paraffin: CDNF Antibody [NBP1-76834] - Staining of CDNF in mouse brain tissue with at 5 ug/mL.
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Applications for CDNF Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

2-4 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CDNF

The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6-OHDA)-induced degeneration of dopaminergic neurons in a rat model of Parkinson's disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinson's disease. At least two isoforms of CDNF are known to exist. This antibody does not cross-react with MANF.

Long Name

Conserved Dopamine Neurotrophic Factor

Alternate Names

ARMETL1

Gene Symbol

CDNF

UniProt

Q49AH0 (Human)

Additional CDNF Products

Product Documents for CDNF Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CDNF Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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