CDX2 Antibody (CDX2/2214) - Azide and BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-08650
![Immunohistochemistry-Paraffin: CDX2 Antibody (CDX2/2214) - Azide and BSA Free [NBP3-08650]](https://resources.bio-techne.com/images/products/CDX2-Antibody-CDX2-2214-Immunohistochemistry-Paraffin-NBP3-08650-img0001.jpg "Immunohistochemistry-Paraffin: CDX2 Antibody (CDX2/2214) - Azide and BSA Free [NBP3-08650]")
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Applications
Immunohistochemistry-Paraffin, Protein Array
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # CDX2/2214
Format
Azide and BSA Free
Concentration
1 mg/ml
Product Summary for CDX2 Antibody (CDX2/2214) - Azide and BSA Free
Immunogen
Recombinant human full-length CDX2 protein (Uniprot: Q99626)
Localization
Nuclear
Specificity
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
Marker
GI Epithelial Marker
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Theoretical MW
40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Description
1.0 mg/ml of antibody purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS WITHOUT BSA & azide. Also available at 200 ug/ml WITH BSA & azide (NBP3-07426).
Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.
Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.
Scientific Data Images for CDX2 Antibody (CDX2/2214) - Azide and BSA Free
Immunohistochemistry-Paraffin: CDX2 Antibody (CDX2/2214) - Azide and BSA Free [NBP3-08650]
Immunohistochemistry-Paraffin: CDX2 Antibody (CDX2/2214) [NBP3-08650] - Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with CDX2 Mouse Monoclonal Antibody (CDX2/2214).![Protein Array: CDX2 Antibody (CDX2/2214) - Azide and BSA Free [NBP3-08650]](https://resources.bio-techne.com/images/products/CDX2-Antibody-CDX2-2214-Protein-Array-NBP3-08650-img0002.jpg "Protein Array: CDX2 Antibody (CDX2/2214) - Azide and BSA Free [NBP3-08650]")
Protein Array: CDX2 Antibody (CDX2/2214) - Azide and BSA Free [NBP3-08650]
Protein Array: CDX2 Antibody (CDX2/2214) [NBP3-08650] - Analysis of Protein Array containing more than 19,000 full-length human proteins using CDX2 Mouse Monoclonal Antibody (CDX2/2214).Applications for CDX2 Antibody (CDX2/2214) - Azide and BSA Free
Application
Recommended Usage
Immunohistochemistry-Paraffin
1-2 ug/ml
Application Notes
Immunohistochemistry Formalin-fixed: 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 for 45 min at 95C followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
10 mM PBS
Format
Azide and BSA Free
Preservative
No Preservative
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Background: CDX2
Long Name
Caudal-type Homeobox Transcription Factor 2
Alternate Names
CDX3
Gene Symbol
CDX2
Additional CDX2 Products
Product Documents for CDX2 Antibody (CDX2/2214) - Azide and BSA Free
Product Specific Notices for CDX2 Antibody (CDX2/2214) - Azide and BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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