CDYL Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB300-874

Novus Biologicals, part of Bio-Techne
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NB300-874
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Porcine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all CDYL Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-SMLKYLQRKIDEF corresponding to C-Terminus according to NP_004815.3, NP_001137442.1, NP_001137443.1.

Specificity

This antibody is expected to recognize both eported isoforms NP_004815.3; NP_001137442.1; NP_001137443.1). Variants (NP_001137442.1; NP_001137443.1) encode the same isoform.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for CDYL Antibody

Western Blot: CDYL Antibody [NB300-874]

Western Blot: CDYL Antibody [NB300-874]

Western Blot: CDYL Antibody [NB300-874] - (1ug/ml) of Human Testes lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Applications for CDYL Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:4000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 75 kDa band observed in human testis lysates is reported in scientific literature (PMID: 12072557). An additional band of unknown identity was also consistently observed at 26 kDa. This band was successfully blocked by incubation with the immunizing peptide.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CDYL

Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene.

Alternate Names

CDYL1bA620A17.2 (chromodomain protein, Y chromosome-like), CDY-like, CDY-like, autosomal, chromodomain protein, Y chromosome-like, chromodomain protein, Y-like, chromodomain Y-like protein, DKFZp586C1622, EC 2.3.1.48, MGC131936, testis-specific chromodomain Y-like protein

Entrez Gene IDs

9425 (Human); 12593 (Mouse)

Gene Symbol

CDYL

UniProt

NP_004815 (Human)

Additional CDYL Products

Product Documents for CDYL Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CDYL Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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