CEACAM6/CD66c Antibody (4Z3V7)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16625

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-16625-100ul
NBP3-16625-20ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 4Z3V7

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CEACAM-6/CD66c Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human CEACAM6/CD66c (P40199). LTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVPTISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQ

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CEACAM6/CD66c Antibody (4Z3V7)

Western Blot: CEACAM6/CD66c Antibody (4Z3V7) [NBP3-16625]

Western Blot: CEACAM6/CD66c Antibody (4Z3V7) [NBP3-16625]

Western Blot: CEACAM6/CD66c Antibody (4Z3V7) [NBP3-16625] - Analysis of extracts of various cell lines, using CEACAM6/CD66c Rabbit mAb (NBP3-16625) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Immunocytochemistry/ Immunofluorescence: CEACAM6/CD66c Antibody (4Z3V7) [NBP3-16625]

Immunocytochemistry/ Immunofluorescence: CEACAM6/CD66c Antibody (4Z3V7) [NBP3-16625]

Immunocytochemistry/Immunofluorescence: CEACAM6/CD66c Antibody (4Z3V7) [NBP3-16625] - Immunofluorescence analysis of mouse large intestine cells using CEACAM6/CD66c Rabbit mAb (NBP3-16625) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunocytochemistry/ Immunofluorescence: CEACAM6/CD66c Antibody (4Z3V7) [NBP3-16625]

Immunocytochemistry/ Immunofluorescence: CEACAM6/CD66c Antibody (4Z3V7) [NBP3-16625]

Immunocytochemistry/Immunofluorescence: CEACAM6/CD66c Antibody (4Z3V7) [NBP3-16625] - Immunofluorescence analysis of rat rectum cells using CEACAM6/CD66c Rabbit mAb (NBP3-16625) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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Applications for CEACAM6/CD66c Antibody (4Z3V7)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50 - 1:200

Western Blot

1:500 - 1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CEACAM-6/CD66c

CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glycoprotein (PSG1-PSG11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. CEACAM 6 expression is strongly up-regulated already during early stages of adenocarcinoma formation e.g. in colon. The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.

Long Name

Carcinoembryonic Antigen-related Cell Adhesion Molecule 6

Alternate Names

CD66c, CEACAM6, CEAL, NCA

Gene Symbol

CEACAM6

Additional CEACAM-6/CD66c Products

Product Documents for CEACAM6/CD66c Antibody (4Z3V7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CEACAM6/CD66c Antibody (4Z3V7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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