CEACAM6/CD66c Antibody (B6.2) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-09125

Novus Biologicals, part of Bio-Techne
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NBP3-09125
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # B6.2

Format

BSA Free

Concentration

1 mg/ml

View all CEACAM-6/CD66c Antibodies »

Product Specifications

Immunogen

Extracts from human breast carcinoma cells

Specificity

The mouse monoclonal antibody B6.2 recognizes a conformationally dependent epitope of native CD66c, a GPI-anchored extracellular glycoprotein expressed on granulocytes and epithelial cells.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for CEACAM6/CD66c Antibody (B6.2) - BSA Free

Flow Cytometry: CEACAM6/CD66c Antibody (B6.2) - BSA Free [NBP3-09125]

Flow Cytometry: CEACAM6/CD66c Antibody (B6.2) - BSA Free [NBP3-09125]

Flow Cytometry: CEACAM6/CD66c Antibody (B6.2) [NBP3-09125] - Separation of neutrophil granulocytes stained anti-human CD66c (B6.2) purified antibody (concentration in sample 3 ug/ml, GAM APC, red-filled) from neutrophil granulocytes unstained by primary antibody (GAM APC, black-dashed) in flow cytometry analysis (surface staining).
Flow Cytometry: CEACAM6/CD66c Antibody (B6.2) - BSA Free [NBP3-09125]

Flow Cytometry: CEACAM6/CD66c Antibody (B6.2) - BSA Free [NBP3-09125]

Flow Cytometry: CEACAM6/CD66c Antibody (B6.2) [NBP3-09125] - Surface staining pattern of human peripheral whole blood stained using anti-human CD66c (B6.2) purified antibody (concentration in sample 3 ug/ml, GAM APC).

Applications for CEACAM6/CD66c Antibody (B6.2) - BSA Free

Application
Recommended Usage

Flow Cytometry

3-12 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CEACAM-6/CD66c

CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glycoprotein (PSG1-PSG11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. CEACAM 6 expression is strongly up-regulated already during early stages of adenocarcinoma formation e.g. in colon. The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.

Long Name

Carcinoembryonic Antigen-related Cell Adhesion Molecule 6

Alternate Names

CD66c, CEACAM6, CEAL, NCA

Gene Symbol

CEACAM6

Additional CEACAM-6/CD66c Products

Product Documents for CEACAM6/CD66c Antibody (B6.2) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CEACAM6/CD66c Antibody (B6.2) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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