CENPJ Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-50018

Novus Biologicals, part of Bio-Techne
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NBP1-50018
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Chimpanzee (100%). Backed by our 100% Guarantee.

Applications

Immunoprecipitation (Negative), Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all CENPJ Antibodies »

Product Summary for CENPJ Antibody

Immunogen

The immunogen for this product maps to a region between residue 675 and 725 of human Centromere Protein J using the numbering given in entry NP_060921.2 (GeneID 55835).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CENPJ Antibody

Western Blot: CENPJ Antibody [NBP1-50018]

Western Blot: CENPJ Antibody [NBP1-50018]

Western Blot: CENPJ Antibody [NBP1-50018] - Whole cell lysate (5, 15 and 50 ug) from HeLa cells. Antibody used at 0.04 ug/ml.

Applications for CENPJ Antibody

Application
Recommended Usage

Western Blot

1:2000-1:10000
Application Notes
Immunoprecipitation Not recommended. Western blot of lysates performed using standard western blot reagents and 4-8% SDS-PAGE.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: CENPJ

This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation.

Alternate Names

BM032, CENP-J, centromere protein J, Centrosomal P4.1-associated protein, CPAPMCPH6, LAG-3-associated protein, LAPSCKL4, LIP1microcephaly, primary autosomal recessive 6, LYST-interacting protein 1, LYST-interacting protein LIP1, LYST-interacting protein LIP7, MGC131581, MGC131582, MGC142222, MGC142224, Sas-4, SASS4

Gene Symbol

CENPJ

Additional CENPJ Products

Product Documents for CENPJ Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CENPJ Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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