CENPO Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76240

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all CENPO Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide from near the center of human CENPO. The immunogen is located within amino acids 170 - 220 of CENPO. Amino Acid Squence: AYSGRKYQADRLQSDF

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CENPO Antibody - BSA Free

Western Blot: CENPO AntibodyBSA Free [NBP1-76240]

Western Blot: CENPO AntibodyBSA Free [NBP1-76240]

Western Blot: CENPO Antibody [NBP1-76240] - mouse kidney tissue lysate with CENPO antibody at (A) 1 and (B) 2 ug/ml.

Applications for CENPO Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CENPO

Accurate chromosome segregation during mitosis requires a kinetochore to assemble correctly at the centromere of each chromatid and form a dynamic interface with the microtubules of the mitotic spindle. The kinetochore assembly includes the multisubunit CENP-H/I complex which can be divided into three functional classes based on phenotype analysis. One of these classes is referred to as the CENP-O class of proteins of which CENPO is the exemplar. These proteins form a stable complex with each other and are required for proper kinetochore function and for recovery from mitotic spindle damage. CENPO has also been shown to be an auto-antigen in a small population of anti-centromere antibodies- (ACA-) positive patients with sclerodoma.

Alternate Names

CENP-OMGC11266, centromere protein O, centromeric protein O, ICEN36, ICEN-36, Interphase centromere complex protein 36, MCM21R

Gene Symbol

CENPO

UniProt

NP_077298 (Human)

Additional CENPO Products

Product Documents for CENPO Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CENPO Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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