CETP Antibody (SR1985)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21657

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21657-100ul
NBP3-21657-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1985

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CETP Antibodies »

Product Summary for CETP Antibody (SR1985)

Immunogen

A synthesized peptide derived from human CETP (Uniprot #: P11597)

Specificity

Detects endogenous levels of total CETP

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CETP Antibody (SR1985)

Western Blot: CETP Antibody (SR1985) [NBP3-21657] -

Western Blot: CETP Antibody (SR1985) [NBP3-21657] - Western blot analysis using NBP3-21657 in human plasma lysate.

Applications for CETP Antibody (SR1985)

Application
Recommended Usage

Immunoprecipitation

1:50

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CETP

It has been proposed that high density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.

Long Name

Cholesteryl Ester Transfer Protein

Alternate Names

BPIFF, HDLCQ10, Lipid Transfer Protein I

Gene Symbol

CETP

Additional CETP Products

Product Documents for CETP Antibody (SR1985)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CETP Antibody (SR1985)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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