cGK2/PRKG2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-05940

Novus Biologicals, part of Bio-Techne
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NBP3-05940-100ul
NBP3-05940-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all cGK2/PRKG2 Antibodies »

Product Summary for cGK2/PRKG2 Antibody

Immunogen

Produced in rabbits immunized with E. coli-derived Human cGK2/PRKG2 fragment.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for cGK2/PRKG2 Antibody

Western Blot: cGK2/PRKG2 Antibody [NBP3-05940]

Western Blot: cGK2/PRKG2 Antibody [NBP3-05940]

Western Blot: cGK2/PRKG2 Antibody [NBP3-05940] - Lane A: 293 Whole Cell LysateLane B: NCI-H460 Whole Cell LysateLysates/proteins at 30 ug per lane.SecondaryGoat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.Developed using the ECL technique.Performed under reducing conditions.Predicted band size:87 kDaObserved band size:81 kDa

Applications for cGK2/PRKG2 Antibody

Application
Recommended Usage

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: cGK2/PRKG2

cGK2/PRKG2, also known as cGMP-dependent protein kinase 2, is 762 amino acids long and approximately 87kDa. cGK2/PRKG2 is a protein kinase that is highly expressed in the brain, intestine and lung. Current research surrounding cGK2/PRKG2 has shown a potential link with several disorders and diseases including cystic fibrosis, gout, malaria, lung cancer, alcoholism, diarrhea, and hyperphenylalaninemia. cGK2/PRKG2 may also interact with PTS, LASP1, YWHAB, MYLK, and PLCB3 in pathways such as cGMP signaling, platelet homeostasis, EDNRB signaling, signaling in gap junctions, nitric oxide metabolism, and eNOS activation and regulation.

Long Name

cGMP-dependent protein kinase 2

Alternate Names

cGK 2, cGK2, cGKII, PRKG2, PRKGR2

Gene Symbol

PRKG2

Additional cGK2/PRKG2 Products

Product Documents for cGK2/PRKG2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for cGK2/PRKG2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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